Livagen dose range
The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 7 published studies are one click away.
Animal studies only Bioregulators Also called KEDA, Lys-Glu-Asp-Ala
Common use ranges
From user guides and clinic write-ups. No drug label exists, and no study has tested these amounts in people. Two community guides agree on 10 to 20 mg a day by mouth for 10 to 30 days. Only one gives an injected amount. Sources are community and vendor guides only. No approved label exists in any country we found, and the published research comes almost entirely from one Russian research group.
Sources disagree, or there are very few. The amounts below come from a small number of guides, and they do not line up well. Treat every number on this page as uncertain, and check each source yourself.
- Half-life
- Not measured in any published study
- How it is taken
- Shot under the skin (subcutaneous), or oral capsule
- How long people use it
- 10 to 20 days in a row, then a break. The course is repeated every 3 to 6 months, which works out to 2 or 3 courses a year.
- Mixing used for the units
- 20 mg vial + 2 mL water. 1 unit on a U-100 insulin syringe = 100 mcg.
Pick your vial size and how much water you add. The units below change to match.
20 mg vial + 2 mL water: 1 unit = 100 mcg
| Tier | Each dose | Syringe units20 mg vial + 2 mL water | How often | Schedule | Vial lastsat this tier |
|---|---|---|---|---|---|
| Starting [1] | 1 mg | 10 units 0.10 mL | once a day | 1 mg under the skin once a day for 10 days, the low end of a 1 to 5 mg range. Injection is the less common form. | 20 days |
| Higher [2] | 5 mg | 50 units 0.50 mL | once a day | 5 mg under the skin once a day for 10 days, the top of the 1 to 5 mg range. | 4 days |
| Oral Typical [3] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day, the low end of the 10 to 20 mg range, for 10 to 30 days. | |
| Oral Higher [4] | 10 mg | Not a syringe dose | 3x a day | 10 mg by mouth 2 to 3 times a day for 10 to 15 days. One guide calls this the Khavinson-style course. | |
| Oral Maintenance [5] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day for 10 days, every 3 to 6 months. | |
| Oral (under the tongue) [6] | 5 mg | Not a syringe dose | 2x a day | 5 to 10 mg under the tongue twice a day. |
Good to know
- Most people take it by mouth. Injection is less common.
- Oral strengths vary a lot by maker. Some packs list capsules, not milligrams, so the label on the box matters more than any range here.
Sources for these amounts
- Starting: Peptide Assistant, Livagen
- Higher: Peptide Assistant, Livagen
- Oral Typical: Peptide Assistant, Livagen · Peptide DB, Livagen
- Oral Higher: Peptide Assistant, Livagen
- Oral Maintenance: Peptide Assistant, Livagen · Peptide DB, Livagen
- Oral (under the tongue): Peptide Assistant, Livagen
How long people use it: Peptide Assistant, Livagen · Peptide DB, Livagen · Khavinson bioregulator guide (IPS News)
Half-life: Timofeeva et al 2005, Adv Gerontol
Take the Livagen chart with you
Get a one-page printable chart for Livagen, with the syringe units for each vial and water mix. We can also email you when a new Livagen study is published.
This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.
See the science: 7 published studies
No human dose data. No published human study of Livagen states an amount given. Every figure on this page comes from animal studies.
Read this first. No PubMed abstract gives an in-animal amount. Rats got it by mouth for 2 weeks, amount unstated. Most studies are in cultured liver cells or lymphocytes from old people. The only stated figure is an IC50 of 20 microM in human serum in a test tube.
Every study used for this page
Proof grade: Animal studies only. No human dose data has been published. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.
| Study | Who was studied | Amount given, as reported | Route | How often | How long | What the authors reported |
|---|---|---|---|---|---|---|
| PMID 16075683Timofeeva et al, Adv Gerontol 2005 | Rat, young and old (n NOT IN ABSTRACT) | Not stated in the abstract | By mouth | NOT IN ABSTRACT | 2 weeks | Gut enzyme activity fell in young rats and rose toward young levels in old rats. Gut enzymes barely broke the peptide down |
| PMID 12942748Kost et al, Izv Akad Nauk Ser Biol 2003 | Human serum in a test tube | IC50 20 microM | Mixed with serum in a test tube | One time | Single assay | Blocked enkephalin-breaking enzymes, no binding to opioid receptors |
| PMID 15926314Brodskii et al, Izv Akad Nauk Ser Biol 2001 | Rat liver cell cultures, rats 1 to 24 months old | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Raised protein synthesis, most in cells from old rats |
| PMID 12577697Riadnova et al, Adv Gerontol 2002 | Rat liver tissue culture | Not stated in the abstract | Added to tissue culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Supported cell structure and repair in liver culture |
| PMID 11713572Khavinson, Bull Exp Biol Med 2001 | Rat liver explants | Not stated in the abstract | Added to tissue culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Stimulated growth of liver explants, tissue-specific |
| PMID 12533768Khavinson et al, Bull Exp Biol Med 2002 | Human lymphocytes from old people, in culture | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Opened up tightly packed chromatin and switched on ribosomal genes |
| PMID 17460203Lezhava and Jokhadze, Ann N Y Acad Sci 2007 | Human lymphocytes from people aged 80 to 91 and 18 to 30, in culture | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Reduced cobalt-induced chromosome damage (3.4% vs 4.2%) and opened chromatin |
How to read the study numbers
- One study, one group. Each figure is what one team chose for its own participants or animals.
- Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
- Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
- Short studies. Many studies ran days or weeks. They do not show what happens over longer use.
Common questions
Is there a human dose for Livagen?
No published human study of Livagen states an amount given. The figures on this page come from animal studies only.
Where do these Livagen numbers come from?
From 7 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Animal studies only.
How long does Livagen stay in the body?
No published study has measured the half-life of Livagen, so nobody knows exactly how long one dose stays in the blood.
Is this a recommendation for how much Livagen to use?
No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.