Bronchogen dose range
The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 6 published studies are one click away.
Animal studies only Bioregulators Also called AEDL, Ala-Glu-Asp-Leu
Common use ranges
From user guides and clinic write-ups. No drug label exists, and no study has tested these amounts in people. Two community guides agree on 10 mg a day for 10 to 20 days by injection, and one gives 10 to 20 mg a day by mouth. Sources are community and vendor guides only. No approved label exists in any country we found, and the published research comes almost entirely from one Russian research group.
Sources disagree, or there are very few. The amounts below come from a small number of guides, and they do not line up well. Treat every number on this page as uncertain, and check each source yourself.
- Half-life
- Not measured in any published study
- How it is taken
- Shot under the skin (subcutaneous), or oral capsule
- How long people use it
- 10 to 20 days in a row, then a break. Repeated every 3 to 6 months, or before cold, flu and allergy season.
- Mixing used for the units
- 20 mg vial + 2 mL water. 1 unit on a U-100 insulin syringe = 100 mcg.
Includes amounts taken by mouth or in the nose. Those are not the same as a shot, see the route in each row below.
Pick your vial size and how much water you add. The units below change to match.
20 mg vial + 2 mL water: 1 unit = 100 mcg
| Tier | Each dose | Syringe units20 mg vial + 2 mL water | How often | Schedule | Vial lastsat this tier |
|---|---|---|---|---|---|
| Typical [1] | 10 mg | 100 units 1.00 mL | once a day | 10 mg under the skin once a day, in the morning, for 10 to 20 days. | 2 days |
| Oral Typical [2] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day, the low end of the 10 to 20 mg range, for 10 to 20 days. | |
| Oral Higher [3] | 20 mg | Not a syringe dose | once a day | 20 mg by mouth once a day, the top of the 10 to 20 mg range. | |
| Oral Maintenance [4] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day for a maintenance course. |
Good to know
- Taken in the morning.
- Injected courses run once a day, every day, for the length of the course. They are not taken all year.
- Oral strengths vary a lot by maker. Some packs list capsules, not milligrams, so the label on the box matters more than any range here.
- A mixed vial is used within about 20 days.
Sources for these amounts
- Typical: Peptide Assistant, Bronchogen · Peptide DB, Bronchogen
- Oral Typical: Peptide DB, Bronchogen
- Oral Higher: Peptide DB, Bronchogen
- Oral Maintenance: Peptide DB, Bronchogen
How long people use it: Peptide Assistant, Bronchogen · Peptide DB, Bronchogen · Khavinson bioregulator guide (IPS News)
Half-life: Khavinson et al 2022, transport of ultrashort peptides (no half-life data)
Take the Bronchogen chart with you
Get a one-page printable chart for Bronchogen, with the syringe units for each vial and water mix. We can also email you when a new Bronchogen study is published.
This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.
See the science: 6 published studies
No human dose data. No published human study of Bronchogen states an amount given. Every figure on this page comes from animal studies.
Read this first. No PubMed abstract gives an in-animal amount. Rat COPD studies ran a 1 month course with the amount unstated. The only stated figure is 0.05 ng/ml in rat lung tissue culture. A Khavinson patent (not peer reviewed) lists 0.2 µg/kg in rats.
Every study used for this page
Proof grade: Animal studies only. No human dose data has been published. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.
| Study | Who was studied | Amount given, as reported | Route | How often | How long | What the authors reported |
|---|---|---|---|---|---|---|
| PMID 26468022Kuzubova et al, Bull Exp Biol Med 2015 | Rat, COPD model from 60 days of NO2 exposure (n NOT IN ABSTRACT) | Not stated in the abstract | NOT IN ABSTRACT | NOT IN ABSTRACT | 1 month | Reversed airway remodeling (goblet cell growth, squamous change, emphysema), restored ciliated cells, raised secretory IgA |
| PMID 30199201Titova et al, Ross Fiziol Zh 2017 | Rat, COPD model from 60 days of NO2 exposure (n NOT IN ABSTRACT) | Not stated in the abstract | NOT IN ABSTRACT | NOT IN ABSTRACT | One course, length NOT IN ABSTRACT | Less neutrophil inflammation in lung fluid, raised secretory IgA and surfactant protein B |
| PMID 17152728Zakutskii et al, Adv Gerontol 2006 | Rat lung tissue explants, young (3 weeks) and old (18 months) | 0.05 ng/ml | Added to tissue culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Stimulated growth of lung explants in young and old rats |
| PMID 22808515Khavinson et al, Bull Exp Biol Med 2012 | Human embryonic bronchial epithelial cell cultures, early and late passage | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Raised differentiation markers CXCL12 and Hoxa3, more in aged cultures |
| PMID 25015171Khavinson et al, Lung 2014 | Human embryonic bronchial epithelial cell cultures, passages 1, 7 and 14 | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Raised Ki67 and Mcl-1 most in old cultures, changed lung differentiation genes, bound DNA in a test tube |
| PMID 21240358Monaselidze et al, Bull Exp Biol Med 2011 | Cell-free test, calf thymus and mouse liver DNA | Molar ratio bronchogen to DNA base pairs 0.01 to 0.055 (effect range), tested up to 1.0 | Mixed with DNA in a test tube | One time | Single measurement | Raised DNA melting temperature by 3.1 C |
How to read the study numbers
- One study, one group. Each figure is what one team chose for its own participants or animals.
- Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
- Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
- Short studies. Many studies ran days or weeks. They do not show what happens over longer use.
Common questions
Is there a human dose for Bronchogen?
No published human study of Bronchogen states an amount given. The figures on this page come from animal studies only.
Where do these Bronchogen numbers come from?
From 6 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Animal studies only.
How long does Bronchogen stay in the body?
No published study has measured the half-life of Bronchogen, so nobody knows exactly how long one dose stays in the blood.
Is this a recommendation for how much Bronchogen to use?
No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.