HGH Fragment 176-191 dose range

The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 6 published studies are one click away.

Animal studies only Metabolic Also called AOD9604, AOD-9604, hGH fragment 177-191

Common use ranges

From user guides and clinic write-ups. No drug label exists, and no study has tested these amounts in people. No drug label. Guides disagree, from 100 mcg to 1 mg a day. No study has tested these amounts in people.

Sources disagree, or there are very few. The amounts below come from a small number of guides, and they do not line up well. Treat every number on this page as uncertain, and check each source yourself.

Half-life
Not measured in any published study
How it is taken
subcutaneous injection
How long people use it
4 to 8 weeks on, then 2 to 4 weeks off.
Mixing used for the units
5 mg vial + 2 mL water. 1 unit on a U-100 insulin syringe = 25 mcg.
Total amount per day, by tier
Starting250 mcg / dayTypical500 mcg / dayHigher1 mg / day
TierEach doseSyringe units5 mg vial + 2 mL waterHow oftenScheduleVial lastsat this tier
Starting [1]250 mcg10 units 0.10 mLonce a day250 mcg once a day, on an empty stomach20 days
Typical [2]250 mcg10 units 0.10 mL2x a day250 mcg twice a day, morning fasted and before a workout or at night10 days
Higher [3]500 mcg20 units 0.20 mL2x a day500 mcg twice a day5 days

Sources for these amounts

  1. Starting: Peptide Protocol Wiki, HGH fragment 176-191 dosing
  2. Typical: Peptide Protocol Wiki, HGH fragment 176-191 dosing
  3. Higher: Peptide Protocol Wiki, HGH fragment 176-191 dosing

How long people use it: Peptide Protocol Wiki, HGH fragment 176-191 dosing

Half-life: Stier et al 2013, J Endocrinol Metab, summary of the six human AOD9604 trials, no pharmacokinetics reported ยท Cox et al 2015, Drug Test Anal, detection and in vitro metabolism of AOD9604

This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.

See the science: 6 published studies

No human dose data. No published human study of HGH Fragment 176-191 states an amount given. Every figure on this page comes from animal studies.

Amounts given to animals in studies

Lowest0.25 mg into the knee joint, once a week (rabbit)
Most used500 micrograms per kilogram by mouth, once a day (rat)
Highest500 micrograms per kilogram by mouth, once a day for 19 days (rat)

Read this first. Company trials in people did happen, up to 54 mg swallowed, but they are published outside PubMed and ClinicalTrials.gov, so no human row is listed here. No study row states an injected amount in people. Company trials in people exist but were not published on PubMed and have no trial registry number, so no human study can be linked here.

Every study used for this page

Proof grade: Animal studies only. No human dose data has been published. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.

StudyWho was studiedAmount given, as reportedRouteHow oftenHow longWhat the authors reported
PMID 11146367Ng et al, Horm Res 2000Rat, obese Zucker500 mcgrams/kgBy mouthOnce a day19 daysWeight gain cut by more than half, insulin sensitivity untouched
PMID 26275694Kwon and Park, Ann Clin Lab Sci 2015Rabbit, 32 with knee arthritis0.25 mg, alone or with 6 mg hyaluronic acidInto the jointOnce a week4 to 7 weeksMore cartilage regrowth than saline, best when paired with hyaluronic acid
PMID 11713213Heffernan et al, Endocrinology 2001Mouse, obese and beta-3 receptor knockoutNot stated in the abstractInto the bellyNot in abstract14 daysCut body weight and fat, but not by acting on the beta-3 receptor
PMID 8358331Wu and Ng, Biochem Mol Biol Int 1993Rat, fat padsNot stated in the abstractNot in abstractNot in abstractNot in abstractBlocked fat building like whole growth hormone, with no fat-release effect
PMID 8118430Wijaya and Ng, Biochem Mol Biol Int 1993Rat fat cells in a dishNot stated in the abstractIn the cell mediumNot in abstractNot in abstractChanged how fat cells take up glucose
PMID 25208511Cox et al, Drug Test Anal 2015Human plasma and urine in a dishNot stated in the abstractIn serum and urine samplesNot applicableNot applicableOne breakdown piece lasts far longer than the peptide itself

How to read the study numbers

  • One study, one group. Each figure is what one team chose for its own participants or animals.
  • Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
  • Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
  • Short studies. Many studies ran days or weeks. They do not show what happens over longer use.

Common questions

Is there a human dose for HGH Fragment 176-191?

No published human study of HGH Fragment 176-191 states an amount given. The figures on this page come from animal studies only.

Where do these HGH Fragment 176-191 numbers come from?

From 6 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Animal studies only.

How long does HGH Fragment 176-191 stay in the body?

No published study has measured the half-life of HGH Fragment 176-191, so nobody knows exactly how long one dose stays in the blood.

Is this a recommendation for how much HGH Fragment 176-191 to use?

No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.

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