AOD-9604 dose range

The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 3 published studies are one click away.

Human trials Metabolic Also called AOD9604, hGH fragment 176-191 (Tyr-modified), Tyr-hGH 177-191

Common use ranges

From published clinic and pharmacy protocols. No drug label exists. Clinic and vendor pages agree well on 250 to 500 mcg once a day, with 300 mcg the most quoted figure. Cycle length varies more.

Half-life
Not on the site yet, being checked
How it is taken
subcutaneous injection
How long people use it
Clinics run 30 day blocks up to 3 in a row, then a month off, or 8 to 16 weeks with check-ins every 4 to 6 weeks.
Mixing used for the units
6 mg vial + 2 mL water. 1 unit on a U-100 insulin syringe = 30 mcg.
Total amount per day, by tier
Starting250 mcg / dayTypical300 mcg / dayHigher500 mcg / day
TierEach doseSyringe units6 mg vial + 2 mL waterHow oftenScheduleVial lastsat this tier
Starting [1]250 mcg8.3 units 0.08 mLonce a day250 mcg once a day in the morningabout 3 weeks
Typical [2]300 mcg10 units 0.10 mLonce a day300 mcg once a day in the morning, before food or exercise20 days
Higher [3]500 mcg16.7 units 0.17 mLonce a day500 mcg once a day, or split morning and evening12 days

Good to know

  • Taken in the morning on an empty stomach.
  • The larger human weight loss trial did not beat placebo, and drug development stopped in 2007.
  • Joint focused protocols run lower, about 200 to 300 mcg, for 4 to 6 weeks.
  • On the WADA banned list.

Sources for these amounts

  1. Starting: Swolverine, AOD 9604 dosage guide
  2. Typical: Perfect B Aesthetic Medicine (Doral, FL), AOD 9604 · Swolverine, AOD 9604 dosage guide
  3. Higher: Swolverine, AOD 9604 dosage guide

How long people use it: Perfect B Aesthetic Medicine (Doral, FL), AOD 9604 · Menscape Clinic (Bangkok), AOD-9604 · Swolverine, AOD 9604 dosage guide

This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.

See the science: 3 published studies

Amounts given to people in studies

Lowest0.25 mg by mouth once a day for 24 weeks
Most used1 to 30 mg by mouth once a day for 12 weeks
Highest54 mg by mouth once a day for 7 days (IV trials went up to 400 µg/kg one time)

How it was given: By mouth (tablets or capsules), and IV in early trials

No human trial used injection under the skin. Trial details come from a company-linked paper with no PubMed record.

Amounts given to animals in studies

Lowest0.25 mg once a week for 4 weeks, into the knee joint (rabbit)
Most used500 microg/kg once a day for 19 days, by mouth (rat)
Highest500 microg/kg once a day for 19 days, by mouth (rat)

Read this first. The largest trial (502 people, 24 weeks) found no weight loss, and development stopped. All human data come from the maker's own trials, reported in a company-linked journal paper. AOD-9604 was tested in people in several company-run trials, including a larger trial that did not meet its goal. Those trials were not published on PubMed, so they are not in the study table below. The table shows only the published animal studies.

Every study used for this page

Proof grade: Human trials. Tested in randomized human trials. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.

StudyWho was studiedAmount given, as reportedRouteHow oftenHow longWhat the authors reported
PMID 11146367Ng et al, Horm Res 2000Rat, obese Zucker500 mcg/kg body weightBy mouthOnce a day19 daysWeight gain cut by over half, no harm to insulin sensitivity
PMID 11713213Heffernan et al, Endocrinology 2001Mouse, obese, and beta-3 receptor knockout miceNot stated in the abstractInto the bellyDaily (chronic)14 daysLess body weight and body fat in obese mice. No effect in knockout mice
PMID 26275694Kwon and Park, Ann Clin Lab Sci 2015Rabbit, knee osteoarthritis model (n=32)0.25 mg, alone or with 6 mg hyaluronic acidInto the knee jointOnce a week4 weeks (weeks 4 to 7)Better cartilage scores. Best with hyaluronic acid

How to read the study numbers

  • One study, one group. Each figure is what one team chose for its own participants or animals.
  • Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
  • Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
  • Short studies. Many studies ran days or weeks. They do not show what happens over longer use.

Common questions

What amounts of AOD-9604 were used in human studies?

In the studies listed here, people were given from 0.25 mg by mouth once a day for 24 weeks up to 54 mg by mouth once a day for 7 days (IV trials went up to 400 µg/kg one time). The amount used most often was 1 to 30 mg by mouth once a day for 12 weeks. These are what study teams chose for their participants under supervision.

Where do these AOD-9604 numbers come from?

From 3 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Human trials.

Is this a recommendation for how much AOD-9604 to use?

No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.

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