5-Amino-1MQ dose range
The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 5 published studies are one click away.
Animal studies only Metabolic Not a peptide Also called 5A1MQ, 5-amino-1-methylquinolinium, NNMT inhibitor
Common use ranges
From published clinic and pharmacy protocols. No drug label exists. Compounding and telehealth guides agree on 50 mg to start and 50 to 100 mg a day. All of it is scaled from mouse data, with no human trial behind it.
- Half-life
- Not on the site yet, being checked
- How it is taken
- oral capsule
- How long people use it
- Often run 30 to 90 days, or 4 to 12 weeks, then a break.
Includes amounts taken by mouth or in the nose. Those are not the same as a shot, see the route in each row below.
| Tier | Each dose | Syringe units | How often | Schedule | Vial lasts |
|---|---|---|---|---|---|
| Oral Starting [1] | 50 mg | Not a syringe dose | once a day | One 50 mg capsule by mouth once a day | |
| Oral Typical [2] | 50 mg | Not a syringe dose | 2x a day | 50 mg by mouth twice a day, 100 mg total, often with a meal that has some fat | |
| Oral Higher [3] | 100 mg | Not a syringe dose | 2x a day | 100 mg by mouth twice a day. Some compounding protocols list up to 200 mg a dose. |
Good to know
- Usually sold as 50 mg capsules, not vials.
- No human dose trial has been published. The 50 mg figure is scaled from mouse studies that used injections.
- Twice a day is used because no one has measured how long it lasts in people.
Sources for these amounts
- Oral Starting: FormBlends, 5-Amino-1MQ dosage · FormBlends, how to take 5-Amino-1MQ
- Oral Typical: FormBlends, how to take 5-Amino-1MQ · FormBlends, 5-Amino-1MQ dosage
- Oral Higher: FormBlends, how to take 5-Amino-1MQ
How long people use it: FormBlends, how to take 5-Amino-1MQ · FormBlends, 5-Amino-1MQ dosage
Take the 5-Amino-1MQ chart with you
Get a one-page printable chart for 5-Amino-1MQ, with the syringe units for each vial and water mix. We can also email you when a new 5-Amino-1MQ study is published.
This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.
See the science: 5 published studies
No human dose data. No published human study of 5-Amino-1MQ states an amount given. Every figure on this page comes from animal studies.
Amounts given to animals in studies
Read this first. No human study of any kind. Almost every animal study comes from one lab group, several linked to the company developing it. Taken by mouth, only about 3.5% was absorbed in mice.
Every study used for this page
Proof grade: Animal studies only. No human dose data has been published. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.
| Study | Who was studied | Amount given, as reported | Route | How often | How long | What the authors reported |
|---|---|---|---|---|---|---|
| PMID 29155147Neelakantan et al, Biochem Pharmacol 2018 | Mouse, diet-induced obese (n=9 per group) | 20 mg/kg three times a day (60 mg/kg/day total). Dose-finding range 10 to 150 mg/kg/day (PMC full text) | Under the skin | Three times a day | 11 days | Body weight and white fat mass fell, fat cells shrank, cholesterol fell, food intake unchanged |
| PMID 30753815Neelakantan et al, Biochem Pharmacol 2019 | Mouse, 24-month-old, injured leg muscle (n=10 to 13 per group) | 5 and 10 mg/kg | Under the skin (PMC full text) | Twice a day (PMC full text) | 2 weeks, and 4 weeks at 10 mg/kg | More active muscle stem cells, about 2-fold larger fibers, about 70% more peak torque in old mice |
| PMID 35013352Dimet-Wiley et al, Sci Rep 2022 | Mouse, diet-induced obese, switched to low-fat diet (about 8 per group) | 32 mg/kg (PMC full text) | Under the skin (PMC full text) | Once a day (PMC full text) | About 7 weeks (PMC full text) | With a low-fat diet, weight and fat dropped to lean-mouse levels and gut bacteria shifted |
| PMID 39161060Babula et al, Diabetes Obes Metab 2024 | Mouse, diet-induced obese (n=8 per group) | 10 and 32 mg/kg/day (PMC full text) | Under the skin | Once a day | 28 to 30 days | Dose-dependent less weight and fat gain, better insulin response, less fatty liver |
| PMID 39161060Babula et al, Diabetes Obes Metab 2024, PK arm | Mouse (n=3 to 12 per arm) | 5 mg/kg IV, 30 mg/kg oral, 25 mg/kg under the skin (PMC full text) | IV, by mouth, under the skin | One time, and once a day for 5 days (under the skin) | Single dose to 5 days | Half-life 6.3 h IV and about 13 h under the skin. Oral uptake only 3.5% |
How to read the study numbers
- One study, one group. Each figure is what one team chose for its own participants or animals.
- Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
- Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
- Short studies. Many studies ran days or weeks. They do not show what happens over longer use.
Common questions
Is there a human dose for 5-Amino-1MQ?
No published human study of 5-Amino-1MQ states an amount given. The figures on this page come from animal studies only.
Where do these 5-Amino-1MQ numbers come from?
From 5 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Animal studies only.
Is this a recommendation for how much 5-Amino-1MQ to use?
No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.